病例讨论:SLE伴反复呕吐、腹胀、肾积水

2010-09-12 MedSci原创 MedSci原创

来源:中国医学论坛报 作者:南京军区南京总医院 张炯 章海涛 刘志红   病历摘要   患者女,16岁,因“确诊系统性红斑狼疮(SLE)6个月,反复腹泻、呕吐4个月,加重3天”入院。患者因先后出现眼睑及下肢水肿、尿蛋白和尿隐血、多个关节疼痛、血常规三系减少等,于6个月前来我科就诊,并被诊为SLE。其中,SLE疾病活动性指数(SLE-DAI)为11分,肾活检示狼疮性肾炎Ⅳ型[活动性指数(AI)

来源:中国医学论坛报 作者:南京军区南京总医院 张炯 章海涛 刘志红   病历摘要   患者女,16岁,因“确诊系统性红斑狼疮(SLE)6个月,反复腹泻、呕吐4个月,加重3天”入院。患者因先后出现眼睑及下肢水肿、尿蛋白和尿隐血、多个关节疼痛、血常规三系减少等,于6个月前来我科就诊,并被诊为SLE。其中,SLE疾病活动性指数(SLE-DAI)为11分,肾活检示狼疮性肾炎Ⅳ型[活动性指数(AI)6分,慢性指数(CI)0分]。在0.5 g/d甲泼尼龙冲击3天后,患者继续接受30 mg/d泼尼松和0.75 g/d吗替麦考酚酯治疗;后因抽血处感染而停用吗替麦考酚酯,泼尼松减至15 mg/d,口服抗生素后好转出院。   4个月前,患者无明显诱因出现上腹痛伴发热,无腹泻、呕吐,体温最高为39℃,第二次入住我科。检查结果示,肝酶升高、自身免疫性肝病相关抗体阴性。住院期间,患者出现腹胀、腹泻(黄色水样便),大便常规及细菌培养无异常;每天排尿10~15次,双肾B超提示肾盂、上段输尿管积水,膀胱残余尿量约84 ml。患者接受抗感染、止泻等对症治疗,泼尼松增至45 mg/d,消化道症状好转。磁共振成像(M

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    2010-09-14 qindq
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