Stroke:非心源性后循环缺血性卒中后复发性卒中或短暂性脑缺血发作的预测!

2017-06-17 xing.T MedSci原创

由此可见,在某些后循环缺血性卒中患者中其复发缺血性卒中或TIA的风险较高。对于这些患者需要尽早进行紧急评估与预防治疗。

后循环缺血性卒中通常被认为是一种预后不良的疾病。然而,目前尚无有效的量表来预测后循环缺血性卒中后的复发卒中。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在明确可以帮助预测复发性脑缺血发作的临床或放射学指标。

研究人员前瞻性地纳入了723例发病小于7天的非心源性后循环缺血性卒中患者。研究人员评估了卒中危险因素、入院症状和体征、急性脑梗死的位置分布和受累大脑动脉,以及1年内的任何复发性或短暂性脑缺血发作(TIA)。研究人员采用Cox回归分析来确定后循环缺血性卒中后1年内复发缺血性卒中或TIA相关的危险因素。

该研究共纳入了40例(5.5%)后循环缺血性卒中后1年内发生复发缺血性卒中或TIA的患者。研究人员采用多因素Cox回归分析确定了吞咽困难(风险比[HR]为4.16;95%可信区间[CI]为1.69-10.2;P=0.002)、卒中前3个月反复短暂性脑缺血发作(HR为15.4;95%CI为5.55-42.5;P<0.0001),病变血管狭窄超过70%(HR为7.91;95%CI为1-62.6;P=0.05),多发梗死(HR为5.38;95%CI为1.25-23.3;P=0.02)作为复发缺血性脑卒中或TIA的独立预测因素,但出院时进行抗血栓治疗不是(HR为3.06;95%CI为1.09-8.58;P=0.03)。

由此可见,在某些后循环缺血性卒中患者中其复发缺血性卒中或TIA的风险较高。对于这些患者需要尽早进行紧急评估与预防治疗。

原始出处:

Changqing Zhang,et al. Prediction of Recurrent Stroke or Transient Ischemic Attack After Noncardiogenic Posterior Circulation Ischemic Stroke.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.116.016285

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1806158, encodeId=27151806158e4, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Fri Nov 24 14:24:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800816, encodeId=5ca718008165a, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=, 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style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Nov 02 19:24:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909636, encodeId=4fbf190963686, content=<a href='/topic/show?id=8f1f42518d8' target=_blank style='color:#2F92EE;'>#复发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42518, encryptionId=8f1f42518d8, topicName=复发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Mar 31 05:24:00 CST 2018, time=2018-03-31, status=1, ipAttribution=), 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createdName=cqlidoudou, createdTime=Mon Jun 19 07:24:00 CST 2017, time=2017-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593442, encodeId=24c21593442ca, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Mon Jun 19 07:24:00 CST 2017, time=2017-06-19, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1806158, encodeId=27151806158e4, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Fri Nov 24 14:24:00 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1800816, encodeId=5ca718008165a, content=<a href='/topic/show?id=8a3be319614' target=_blank style='color:#2F92EE;'>#短暂性脑缺#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73196, encryptionId=8a3be319614, topicName=短暂性脑缺)], attachment=null, authenticateStatus=null, createdAvatar=, 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style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Nov 02 19:24:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909636, encodeId=4fbf190963686, content=<a href='/topic/show?id=8f1f42518d8' target=_blank style='color:#2F92EE;'>#复发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42518, encryptionId=8f1f42518d8, topicName=复发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Mar 31 05:24:00 CST 2018, time=2018-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=217060, encodeId=234d21e06005, content=文章很好,拜读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jun 30 10:33:17 CST 2017, time=2017-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289197, encodeId=5183128919ef6, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, 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  7. 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  8. 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createdName=cqlidoudou, createdTime=Mon Jun 19 07:24:00 CST 2017, time=2017-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593442, encodeId=24c21593442ca, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Mon Jun 19 07:24:00 CST 2017, time=2017-06-19, status=1, ipAttribution=)]
    2017-06-30 1e10c84am36(暂无匿称)

    文章很好,拜读受益

    0

  9. 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  10. 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style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Nov 02 19:24:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1909636, encodeId=4fbf190963686, content=<a href='/topic/show?id=8f1f42518d8' target=_blank style='color:#2F92EE;'>#复发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42518, encryptionId=8f1f42518d8, topicName=复发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sat Mar 31 05:24:00 CST 2018, time=2018-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=217060, encodeId=234d21e06005, content=文章很好,拜读受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Jun 30 10:33:17 CST 2017, time=2017-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289197, encodeId=5183128919ef6, content=<a href='/topic/show?id=cd268500578' target=_blank style='color:#2F92EE;'>#脑缺血#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85005, encryptionId=cd268500578, topicName=脑缺血)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=845e216, createdName=cqlidoudou, createdTime=Mon Jun 19 07:24:00 CST 2017, time=2017-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593442, encodeId=24c21593442ca, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Mon Jun 19 07:24:00 CST 2017, time=2017-06-19, status=1, ipAttribution=)]
    2017-06-19 mhm295

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