ACS Appl Mater & Inter:科学家研制出新型骨组织仿生支架材料

2014-03-17 黄辛 中国科学报

记者从东华大学获悉,该校生物科学与技术研究所张彦中教授课题组利用电纺丝技术结合新型的形状记忆聚合物,研制出一种具有形状记忆效应的组织工程仿生支架。相关研究成果日前发表于《美国化学会—应用材料与界面》。美国化学会周刊《化学化工新闻》对此也进行了专门报道。 骨折是常见的骨科伤病,约有10%的伤者会因骨折愈合钢钉取出后在骨头上留下骨钉孔而有再骨折的危险。如何降低再骨折发生率,对骨的力学缺陷进行“补强”

记者从东华大学获悉,该校生物科学与技术研究所张彦中教授课题组利用电纺丝技术结合新型的形状记忆聚合物,研制出一种具有形状记忆效应的组织工程仿生支架。相关研究成果日前发表于《美国化学会—应用材料与界面》。美国化学会周刊《化学化工新闻》对此也进行了专门报道。

骨折是常见的骨科伤病,约有10%的伤者会因骨折愈合钢钉取出后在骨头上留下骨钉孔而有再骨折的危险。如何降低再骨折发生率,对骨的力学缺陷进行“补强”?

为此,张彦中课题组在2002年开始了骨修复生物材料的研究。该团队最新研制出的组织工程仿生支架不仅具有仿生天然骨纳米纤维的结构特点、促进骨细胞生长的成骨性能,而且能在体温作用下发生形状记忆恢复,紧密填充钉道缺损部位,降低骨折间隙。同时,该支架还有可生物降解的特性,能较好与原来的骨组织相容,不需要再次取出,可达到原位再生骨组织的目的。

张彦中表示,团队下一步将开展生物体内实验,进一步验证该新型骨植入支架在生物体内修复骨缺损的实际功效。据悉,目前该团队已经和浙江大学、上海市第一人民医院有关专家开展了深入合作。

原始出处

Bao M1, Lou X, Zhou Q, Dong W, Yuan H, Zhang Y.Electrospun Biomimetic Fibrous Scaffold from Shape Memory Polymer of PDLLA-co-TMC for Bone Tissue Engineering.ACS Appl Mater Interfaces. 2014 Feb 26

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2076325, encodeId=ef6520e63258c, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Tue Jul 22 22:26:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663215, encodeId=328c16632151a, content=<a href='/topic/show?id=f5c025606c2' target=_blank style='color:#2F92EE;'>#仿生支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25606, encryptionId=f5c025606c2, topicName=仿生支架)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1325580228, createdName=zjshifan_98647314, createdTime=Wed Oct 15 17:26:00 CST 2014, time=2014-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775788, encodeId=d5f21e75788d1, content=<a href='/topic/show?id=a7235e107b2' target=_blank style='color:#2F92EE;'>#支架材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57107, encryptionId=a7235e107b2, topicName=支架材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce4f38811844, createdName=tidiq, createdTime=Sun Apr 20 10:26:00 CST 2014, time=2014-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279047, encodeId=315912e90476b, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Wed Mar 19 00:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2076325, encodeId=ef6520e63258c, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Tue Jul 22 22:26:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663215, encodeId=328c16632151a, content=<a href='/topic/show?id=f5c025606c2' target=_blank style='color:#2F92EE;'>#仿生支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25606, encryptionId=f5c025606c2, topicName=仿生支架)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1325580228, createdName=zjshifan_98647314, createdTime=Wed Oct 15 17:26:00 CST 2014, time=2014-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775788, encodeId=d5f21e75788d1, content=<a href='/topic/show?id=a7235e107b2' target=_blank style='color:#2F92EE;'>#支架材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57107, encryptionId=a7235e107b2, topicName=支架材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce4f38811844, createdName=tidiq, createdTime=Sun Apr 20 10:26:00 CST 2014, time=2014-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279047, encodeId=315912e90476b, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Wed Mar 19 00:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2076325, encodeId=ef6520e63258c, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Tue Jul 22 22:26:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663215, encodeId=328c16632151a, content=<a href='/topic/show?id=f5c025606c2' target=_blank style='color:#2F92EE;'>#仿生支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25606, encryptionId=f5c025606c2, topicName=仿生支架)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1325580228, createdName=zjshifan_98647314, createdTime=Wed Oct 15 17:26:00 CST 2014, time=2014-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775788, encodeId=d5f21e75788d1, content=<a href='/topic/show?id=a7235e107b2' target=_blank style='color:#2F92EE;'>#支架材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57107, encryptionId=a7235e107b2, topicName=支架材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce4f38811844, createdName=tidiq, createdTime=Sun Apr 20 10:26:00 CST 2014, time=2014-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279047, encodeId=315912e90476b, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Wed Mar 19 00:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2076325, encodeId=ef6520e63258c, content=<a href='/topic/show?id=940410181964' target=_blank style='color:#2F92EE;'>#骨组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101819, encryptionId=940410181964, topicName=骨组织)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Tue Jul 22 22:26:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663215, encodeId=328c16632151a, content=<a href='/topic/show?id=f5c025606c2' target=_blank style='color:#2F92EE;'>#仿生支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25606, encryptionId=f5c025606c2, topicName=仿生支架)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1325580228, createdName=zjshifan_98647314, createdTime=Wed Oct 15 17:26:00 CST 2014, time=2014-10-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775788, encodeId=d5f21e75788d1, content=<a href='/topic/show?id=a7235e107b2' target=_blank style='color:#2F92EE;'>#支架材料#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57107, encryptionId=a7235e107b2, topicName=支架材料)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce4f38811844, createdName=tidiq, createdTime=Sun Apr 20 10:26:00 CST 2014, time=2014-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1279047, encodeId=315912e90476b, content=<a href='/topic/show?id=316d1882bc' target=_blank style='color:#2F92EE;'>#ACS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Wed Mar 19 00:26:00 CST 2014, time=2014-03-19, status=1, ipAttribution=)]
    2014-03-19 yaanren

相关资讯

董纪元:老喝大酒,容易“泡”坏关节

董纪元 董纪元,解放军总医院主任医师、教授,亚洲骨科人工关节学会委员,华裔骨科学会关节外科分会理事 35岁的李先生是一名项目经理,天天忙着出差、应酬,经常为了一个项目与客户喝上十顿八顿酒。去年开始,他老觉得腿疼,但症状时轻时重,他以为是太过劳累导致的,就没当回事儿。可这半年来越发严重,去医院经检查发现,他患上了双侧股骨头坏死。 酒在中国的社交中担负着重要角色,商务活动、家