Heart:慢性心力衰竭患者的社会经济剥夺和临床结局之间的相关性分析!

2018-02-02 xing.T MedSci原创

由此可见,CHF患者社会经济剥夺与因过度非心血管事件所致的死亡和住院风险增加相关。

近日,在心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员旨在描述慢性心力衰竭(CHF)患者社会经济剥夺与不良结局之间的关系。

研究人员前瞻性地观察了1802例左心室射血分数(LVEF)≤45%的CHF患者,这些患者在2006年至2014年期间被英国的四家医院所招募。研究人员评估了英国多重剥夺指数(IMD)定义的社会经济剥夺与模式特异性死亡率(平均随访4年)、特定模式住院和住院累计时间(1 年后)之间的相关性。

研究人员发现居住在最富和最贫困地区患者之间平均IMD得分差异为45分。社会经济剥夺与年龄、性别和合并症有关,但与CHF症状、LVEF或处方药物治疗无关。IMD评分与年龄性别调整后的全因死亡率(IMD评分每增加10个单位风险增加6%;95%可信区间为2%-10%;P=0.004)和非心血管死亡率(IMD评分每增加10个单位风险增加9%;95%可信区间为3%-16%;P=0.003)相关,而与心血管死亡率无关。全因住院,但不是心衰特异性住院,在最贫困的患者中也较普遍。总的来说,在1 年随访期间,患者住院时间累计为3.3天,并且IMD评分与年龄和性别调整后的住院累计时间相关(IMD评分每增加10个单位住院累计时间增加4%,95%可信区间为3%-6%;P<0.0005)。

由此可见,CHF患者社会经济剥夺与因过度非心血管事件所致的死亡和住院风险增加相关。

原始出处:


Klaus K Witte,et al. Socioeconomic deprivation and mode-specific outcomes in patients with chronic heart failure. Heart. 2017. http://dx.doi.org/10.1136/heartjnl-2017-312539

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  5. 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  6. 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style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Feb 04 01:55:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523595, encodeId=a6a5152359557, content=<a href='/topic/show?id=f6f1e2533e3' target=_blank style='color:#2F92EE;'>#相关性分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72533, encryptionId=f6f1e2533e3, topicName=相关性分析)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad8f11536374, createdName=anminleiryan, createdTime=Sun Feb 04 01:55:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562815, encodeId=dee5156281592, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Sun Feb 04 01:55:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616814, encodeId=3a781616814a3, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Sun Feb 04 01:55:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284537, encodeId=482328453e75, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Fri Feb 02 21:37:51 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-04 zhaojie88
  7. 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createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Sun Feb 04 01:55:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284537, encodeId=482328453e75, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Fri Feb 02 21:37:51 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
  8. 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    2018-02-04 slcumt
  9. 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    2018-02-02 衣带渐宽

    学习

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Eur Heart J:心脏衰竭患者视网膜微血管功能障碍的检测手段!

对闪烁光反应性的视网膜微血管扩张功能在CHF患者中有所受损。RVA可能是一种新的并且有用的方法,以无创和无辐射的方式来监测心力衰竭患者的血管异常。