美国非酒精性脂肪性肝病诊断与治疗临床实践指南简介

2022-09-10 上海交通大学医学院附属新华医院消化内科 实用肝脏病杂志

非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是慢性肝病最常见的病因,影响全球25%的人口。尽管当前NAFLD患病率仍在不断增高,但公众对该病的认知

中文标题:

美国非酒精性脂肪性肝病诊断与治疗临床实践指南简介

发布日期:

2022-09-10

简要介绍:

非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是慢性肝病最常见的病因,影响全球25%的人口。尽管当前NAFLD患病率仍在不断增高,但公众对该病的认知有限,仅5%NAFLD患者知道自己患病。12%~14%以上NAFLD患者为非酒精性脂肪性肝炎(nonalcoholic steatohepatitis,NASH),25%左右NASH患者可发展为进展期肝纤维化、肝硬化,甚至肝细胞癌(hepatocellular carcinoma,HCC)。在美国,NASH已成为HCC的首要病因和肝脏移植的第二大适应证。NAFLD与代谢心血管危险因素互为因果,肥胖和2型糖尿病(type 2 diabetes mellitus,T2DM)患者NASH及其相关肝纤维化发病风险增加2~3倍。此外,NAFLD还是动脉粥样硬化性心脑血管疾病的独立危险因素,冠心病和脑卒中是NAFLD患者死亡的首要原因,肥胖、胰岛素抵抗、T2DM、高血压、血脂异常进一步增加了NAFLD患者心血管疾病风险。 

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    2023-03-28 ms4000001650519349 来自重庆

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    2022-10-24 delianjihui

    感谢分享

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    2022-10-24 delianjihui

    学习受益

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