The disciplines of Biochemistry and Molecular Biology have greatly advanced in the last quarter century. This new knowledge has made significant contributions to the advancement of a wide range of subjects including medicine, genetics, immunology, developmental biology, and biophysics. Investigators in a wide range of disciplines increasingly require an appreciation of the significance of current biochemical and molecular biology advances. Likewise, members of the biochemical and molecular biology community seek understanding of advances in areas remote from their own specialties.