This journal, Science in One Health, provides a platform that disseminates knowledge, real-world research findings and lessons learnt from programmes on health for the human-animal-environmental interface at the local, regional and global levels, in order to reduce the inequity of health issues in the world and promote more advanced researches on One Health. Such a mission is supported by sharing of consistent ideas on emerging topics of interactions between human health, animal health and environmental health, based on the principle of "One World, One Health".

This journal focuses on the One Health issues, including governance capacity, zoonotic diseases, antimicrobial resistance, food safety and food security, vector-borne diseases, environmental contamination, global climate changes, and other health threats shared by people, animals, plants, and the environment. In addition, this journal discusses global health issues, especially, worldwide health improvement including mental health, reduction of disparities, technical assistance & development, global health security & policy, and protection against global threats that disregard national borders.