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Histopathological growth patterns of neuroendocrine tumor liver metastases

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (3)

Histopathological growth patterns (HGPs) of liver metastases represent a potential biomarker for prognosis after resection. They have never been studi......

Treating colorectal peritoneal metastases with an injectable cytostatic loaded supramolecular hydrogel in a rodent animal model

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (3)

Patients with peritoneal metastases (PM) of colorectal cancer have a very poor outcome. Intraperitoneal delivery of chemotherapy is the preferred rout......

Platycodin D represses β-catenin to suppress metastasis of cetuximab-treated KRAS wild-type colorectal cancer cells

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (4)

Cetuximab, an epidermal growth factor receptor ( EGFR) inhibitor, is extensively used for clinical therapy in KRAS wildtype colorectal cancer (CRC) pa......

Clinical characteristics, treatment, and long-term outcome of patients with brain metastases from thyroid cancer

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (3)

Brain metastases (BM) in patients with thyroid cancer (TC) are rare with an incidence of 1% for papillary and follicular, 3% for medullary and up to 1......

High sensitivity flow cytometry immunophenotyping increases the diagnostic yield of malignant pleural effusions

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (6)

Diagnosing malignant pleural effusions (MPE) is challenging when patients lack a history of cancer and cytopathology does not detect malignant cells i......

Sufentanil combined with parecoxib sodium inhibits proliferation and metastasis of HER2-positive breast cancer cells and regulates epithelial-mesenchymal transition

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (2)

BackgroundSufentanil combined with parecoxib sodium is a commonly used postoperative medication for cancer patients. However, the effects of this comb......

Effect of liver metastasis on the efficacy of immune checkpoint inhibitors in cancer patients: a systemic review and meta-analysis

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (4)

Liver metastasis is a frequent phenomenon in advanced tumor disease. Immune checkpoint inhibitors (ICIs) are a new class of therapeutics that can impr......

Association between primary tumor characteristics and histopathological growth pattern of liver metastases in colorectal cancer

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; ()

Introduction: The microarchitecture of liver metastases (LMs), or histopathological growth pattern (HGP), has been demonstrated to be a significant pr......

Ketogenic diet does not promote triple-negative and luminal mammary tumor growth and metastasis in experimental mice

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; ()

Ketogenic diets (KDs) can improve the well-being and quality of life of breast cancer patients. However, data on the effects of KDs on mammary tumors ......

Repurposing fluphenazine to suppress melanoma brain, lung and bone metastasis by inducing G0/G1 cell cycle arrest and apoptosis and disrupting autophagic flux

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (2)

Brain metastasis is the main cause of treatment failure and melanoma-related death. Inadequate concentrations of therapeutic drugs in the brain due to......

Clinical relevance of biomarker discordance between primary breast cancers and synchronous axillary lymph node metastases

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (4)

Clinical decision-making for patients with breast cancer (BC) is still primarily based on biomarker characteristics of the primary tumor, together wit......

Development and adaptations of the Graded Prognostic Assessment (GPA) scale: a systematic review

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (6)

The Graded Prognostic Assessment (GPA) score has the best accuracy among prognostic scales for patients with brain metastases (BM). A wide range of GP......

Brain metastases from hepatopancreatobiliary malignancies

期刊: CLINICAL & EXPERIMENTAL METASTASIS, 2023; 40 (2)

While colorectal and gastroesophageal cancer represent the two gastrointestinal (GI) tumor entities with the highest incidence of brain metastatic (BM......

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