期刊： MITOCHONDRION, 2022; 64 ()
Respiratory Complex I is the site of a large fraction of the mutations that appear to cause mitochondrial disease. Seven of its subunits are mitochond......
期刊： MITOCHONDRION, 2022; 67 ()
The low cerebral metabolic rate of oxygen despite the relatively preserved perfusion in Alzheimer's disease (AD) patients' medial temporal lobes sugge......
期刊： MITOCHONDRION, 2022; 63 ()
Several drug targets have been amenable to drug discovery pursuit not until the characterization of the mitochondrial permeability transition pore (MP......
期刊： MITOCHONDRION, 2022; 67 ()
TRPV4 is associated with the development of neuropathic pain, sensory defects, muscular dystrophies, neuro-degenerative disorders, Charcot Marie Tooth......
期刊： MITOCHONDRION, 2022; 64 ()
Mitochondrial diseases are a group of genetic disorders characterized by dysfunctional mitochondria. Within eukaryotic cells, mitochondria contain the......
期刊： MITOCHONDRION, 2022; 64 ()
Mitochondrial permeability transition pore (mPTP) is a channel that opens at the inner mitochondrial membrane under conditions of stress. Sirtuin 3 (S......
期刊： MITOCHONDRION, 2022; 66 ()
Breast cancer is the most common cancer in women worldwide. MicroRNAs (miRNAs) are non-coding RNAs that are involved in the post-transcriptional regul......
期刊： MITOCHONDRION, 2022; 67 ()
As a key regulator of innate immunity, mitochondrial function is essential to maintain antiviral activities. Common mitochondrial DNA variants (haplog......
期刊： MITOCHONDRION, 2022; 63 ()
Iron deficiency is observed in nearly half of the heart failure patients whilst closely correlated with mitochondrial dysfunction. Besides the structu......
期刊： MITOCHONDRION, 2022; 66 ()
Mitochondria are one of the central organelles involved in cellular energy metabolism and play a regulatory role in various human pathologies ranging ......
期刊： MITOCHONDRION, 2022; 62 ()
Mitochondrial DNA (mtDNA) associated mitochondrial diseases hold a crucial position but comprehensive and systematic studies are relatively rare. Amon......
期刊： MITOCHONDRION, 2022; 63 ()
Mitochondrial dysfunction has been defined as a reduced efficiency of mitochondria to produce ATP given by a loss of mitochondrial membrane potential,......
期刊： MITOCHONDRION, 2022; 64 ()
Alzheimer's disease (AD) is a leading neurodegenerative pathology associated with aging worldwide. It is esti-mated that AD prevalence will increase f......
期刊： MITOCHONDRION, 2022; 65 ()
Brown adipose tissue (BAT) mitochondria generate heat via uncoupled respiration due to excessive proton leak through uncoupling proteins (UCPs). We pr......
期刊： MITOCHONDRION, 2022; 67 ()
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also the source of respiratory ATP. Recently published stud......
