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Regorafenib Induces the Apoptosis of Gastrointestinal Cancer-Associated Fibroblasts by Inhibiting AKT Phosphorylation

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

Cancer-associated fibroblasts (CAFs) are a key component of the tumor microenvironment and are essential for tumorigenesis and development. Regorafeni......

JIF:2.983

Mechanobiological Approaches for Stimulating Chondrogenesis of Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (15-16)

Chondrogenesis is the process of differentiation of stem cells into mature chondrocytes. Such a process consists of chemical, functional, and structur......

JIF:2.983

Overexpression of NDST1 Attenuates Fibrotic Response in Murine Adipose-Derived Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (23-24)

Adipose-derived stem cells (ADSCs) hold tremendous potential for treating diseases and repairing damaged tissues. Heparan sulfate (HS) plays various r......

JIF:2.983

Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions of the Knee: A Prospective Clinical Study at 1 Year

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (15-16)

Bone marrow lesions (BMLs) are typical findings in magnetic resonance imaging present in different pathologies, such as spontaneous insufficiency frac......

JIF:2.983

Delineating the Neuropathology of Lysosomal Storage Diseases Using Patient-Derived Induced Pluripotent Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (9-10)

Lysosomal storage diseases (LSDs) are inherited metabolic diseases caused by deficiency of lysosomal enzymes, essential for the normal development of ......

JIF:2.983

Suppressor of Fused Regulation of Hedgehog Signaling is Required for Proper Astrocyte Differentiation

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (23-24)

Hedgehog signaling is essential for vertebrate development; however, less is known about the negative regulators that influence this pathway. Using th......

JIF:2.983

Research Progress of Totipotent Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

Totipotent stem cells (TSCs), can develop into complete organisms, are used in biological fields such as regenerative medicine, mammalian breeding, an......

JIF:2.983

Three-Dimensional Culture of Equine Bone Marrow-Derived Mesenchymal Stem Cells Enhances Anti-Inflammatory Properties in a Donor-Dependent Manner

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (23-24)

Three-dimensional (3D) culture of human mesenchymal stem cells (MSCs) as spheroids enhances the production of important regulators of inflammation: pr......

JIF:2.983

MicroRNA-7a2 is Required for the Development of Pituitary Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14)

The pituitary gland is inhabited by a subpopulation of SOX2(+) stem cells. However, the regulatory mechanisms underlying pituitary stem cell developme......

JIF:2.983

Survival Motor Neuron Enhances Pluripotent Gene Expression and Facilitates Cell Reprogramming

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (21-22)

Survival motor neuron (SMN) plays important roles in snRNP assembly and mRNA splicing. Deficiency of SMN causes spinal muscular atrophy (SMA), a leadi......

JIF:2.983

An Updated View on Temporomandibular Joint Degeneration: Insights from the Cell Subsets of Mandibular Condylar Cartilage

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (15-16)

The high prevalence of temporomandibular joint osteoarthritis (TMJOA), which causes joint dysfunction, indicates the need for more effective methods f......

JIF:2.983

Effects of Recloning on the Telomere Lengths of Mouse Terc(+/-) Nuclear Transfer-Derived Embryonic Stem Cells

期刊: STEM CELLS AND DEVELOPMENT, 2022; 31 (21-22)

Haploinsufficiency of genes that participate in telomere elongation and maintenance processes, such as telomerase RNA component (Terc) and telomere re......

JIF:2.983

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