Regorafenib Induces the Apoptosis of Gastrointestinal Cancer-Associated Fibroblasts by Inhibiting AKT Phosphorylation

Zhang, MJ; Li, XC; Wu, WJ; Gao, JX; Han, Q; Sun, Z; Zhao, RC

Han, Q; Zhao, RC (通讯作者)，Chinese Acad Med Sci, Peking Union Med Coll, Sch Basic Med, Inst Basic Med Sci,Ctr Excellence Tissue Engn,Beij, 5 Dong Dan San Tiao, Beijing 100005, Peoples R China.;Sun, Z (通讯作者)，Chinese Acad Med Sci & Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Oncol, 1 Shuaifuyuan Hutong, Beijing 100730, Peoples R China.

STEM CELLS AND DEVELOPMENT, 2022; 31 (13-14): 383

Abstract

Cancer-associated fibroblasts (CAFs) are a key component of the tumor microenvironment and are essential for tumorigenesis and development. Regorafeni......

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