筛选条件 共查询到500条结果
排序方式
Biological effects triggered by chemical respiratory sensitizers on THP-1 monocytic cells

期刊: TOXICOLOGY IN VITRO, 2023; 90 ()

Respiratory sensitization encompasses a group of diseases that manifest through airway hyperresponsiveness and airflow limitation. Although the concer......

Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes

期刊: TOXICOLOGY IN VITRO, 2023; 90 ()

Flutamide is a non-steroidal anti-androgen agent, which is mainly used for the treatment of prostate cancer. Flutamide is known to cause severe advers......

Tetrazolium-based colorimetric assays underestimat the direct antitumor effects of anti-VEGF agent bevacizumab

期刊: TOXICOLOGY IN VITRO, 2023; 91 ()

The direct antitumor effect of bevacizumab (BEV) has long been debated. Assessment of the direct cytotoxic activities of drugs is usually conducted vi......

MitoQ alleviates triptolide-induced cardiotoxicity via activation of p62/ Nrf2 axis in H9c2 cells

期刊: TOXICOLOGY IN VITRO, 2023; 86 ()

Triptolide (TP) is one of the major components of Tripterygium wilfordii, which is a traditional Chinese medicine widely used in the treatment of vari......

Benzo[b]fluoranthene (B[b]F) affects apoptosis, oxidative stress, mitochondrial membrane potential and expressions of blood-brain barrier markers in microvascular endothelial cells

期刊: TOXICOLOGY IN VITRO, 2023; 86 ()

Exposure to polycyclic aromatic hydrocarbons (PAHs) contributes to the damage of blood-brain barrier. While a number of studies were focused on benzo[......

New gold (III) cyanide complex TGS 121 induces ER stress, proteasome inhibition and death of Ras-hyperactivated cells

期刊: TOXICOLOGY IN VITRO, 2023; 88 ()

Metal-based agents in cancer therapy, like cisplatin and its derivates, have established clinical applications but also can induce serious side effect......

Development of a lung-liver in vitro coculture model for inhalation-like toxicity assessment

期刊: TOXICOLOGY IN VITRO, 2023; 92 ()

Animal models are considered prime study models for inhalation-like toxicity assessment. However, in light of animal experimentation reduction (3Rs), ......

In vitro eye irritation testing models may play pivotal role in effort to pursue mild baby cleansers

期刊: TOXICOLOGY IN VITRO, 2023; 89 ()

In recent years, mild baby cleansers have experienced ever-growing demand from caregivers. In the meantime, formulation developers are in practical ne......

In vitro immune and redox response induced by cationic cellulose-based nanomaterials

期刊: TOXICOLOGY IN VITRO, 2023; 91 ()

Cellulose nanocrystals (CNCs) display remarkable strength and physicochemical properties with significant potential applications. To better understand......

The effects of non-functionalized polystyrene nanoparticles with different diameters on human erythrocyte membrane and morphology

期刊: TOXICOLOGY IN VITRO, 2023; 91 ()

In this study, the potential toxicity of non-functionalized polystyrene nanoparticles (PS-NPs) in human eryth-rocytes has been assessed. The effect of......

Cell cycle and enzymatic activity alterations induced by ROS production in human neuroblastoma cells SH-SY5Y exposed to Fumonisin B1, Ochratoxin A and their combination

期刊: TOXICOLOGY IN VITRO, 2023; 93 ()

The presence of mycotoxins such as Fumonisin B1(FB1) and Ochratoxin A (OTA) in food and feed has become a threat to human and animal health since they......

Comparison of skin decontamination strategies in the initial operational response following chemical exposures

期刊: TOXICOLOGY IN VITRO, 2023; 87 ()

In mass casualty incidents including hazardous chemical skin exposure, decontamination is the primary intervention to avoid systemic uptake of the tox......

Mechanism for inhibition of cytotoxicity of Shiga toxin by luteolin

期刊: TOXICOLOGY IN VITRO, 2023; 87 ()

Enterohemorrhagic or Shiga toxin-producing Escherichia coli is a food-poisoning bacterium that grows in the intestine to produce Shiga toxin (Stx). In......

The methylimidazolium ionic liquid M8OI is a substrate for OCT1 and p-glycoprotein-1 in rat

期刊: TOXICOLOGY IN VITRO, 2023; 88 ()

The methylimidazolium ionic liquid M8OI was recently found to be present in both the environment and man. In this study, M8OI disposition and toxicity......

Synthetic hydrazones: In silico studies and in vitro evaluation of the antileishmania potential

期刊: TOXICOLOGY IN VITRO, 2023; 88 ()

Bioprospecting and synthesis of strategically designed molecules have been used in the search for drugs that can be in leishmaniasis. Hydrazones (HDZ)......

共500条页码: 1/34页15条/页