Mechanism of non-steroidal anti-androgen-induced liver injury: Reactive metabolites of flutamide and bicalutamide activate inflammasomes

Kato, R; Yamada, T; Noda, T; Tanaka, S; Kohda, Y; Ijiri, Y

Kato, R (通讯作者)，Osaka Med & Pharmaceut Univ, Fac Pharm, Dept Cardiovasc Pharmacotherapy & Toxicol, 4-20-1 Nasahara, Takatsuki, Osaka 5691094, Japan.

TOXICOLOGY IN VITRO, 2023; 90 ():

Abstract

Flutamide is a non-steroidal anti-androgen agent, which is mainly used for the treatment of prostate cancer. Flutamide is known to cause severe advers......

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