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Modified tibial transverse transport technique for the treatment of ischemic diabetic foot ulcer in patients with type 2 diabetes

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 29 ()

Background: Ischemic diabetic foot ulcer is one of the terminal complications of diabetes. The high amputation rate, recurrence rate, and treatment co......

Changes in trabecular bone score and bone mineral density in Chinese HIV-Infected individuals after one year of antiretroviral therapy

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 29 ()

Objective: Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) have been associated with reduced bone mineral density (BMD) ......

Jingshu Keli for treating cervical spondylotic radiculopathy: The first multicenter, randomized, controlled clinical trial

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 ()

Background: Jingshu Keli (or Jingshu granules), a traditional Chinese medicine, are widely used for treating cervical spondylotic radiculopathy in Chi......

Role of the miR-133a-5p/FBXO6 axis in the regulation of intervertebral disc degeneration

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 29 ()

Objective: Low back pain is a leading cause of disabilities worldwide, and intervertebral disc degeneration (IVDD)related disorders have been recognis......

The construction of a novel xenograft bovine bone scaffold, (DSS) 6-liposome/CKIP-1 siRNA/calcine bone and its osteogenesis evaluation on skull defect in rats

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 28 ()

Background: Xenograft bone scaffolds have advantages such as mechanical strength, sufficient source and safety. Combined with siRNA properly targeting......

Hepatocyte growth factor overexpression promotes osteoclastogenesis and exacerbates bone loss in CIA mice

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 ()

Background: Hepatocyte growth factor (HGF) is a multifunctional growth factor that promotes various biological processes. However, the effect of HGF o......

Molecular mechanisms of osteogenesis and antibacterial activity of Cu-bearing Ti alloy in a bone defect model with infection in vivo

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 ()

Objective: The antibacterial activity of copper (Cu)-alloy biomaterials has shown a great potential in clinical application. Here, we evaluated the os......

Chondrocyte ferroptosis contribute to the progression of osteoarthritis

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 ()

Background: Osteoarthritis (OA) is a complex process comprised of mechanical load, inflammation, and metabolic factors. It is still unknown that if ch......

Establishment of near and non isometric anterior cruciate ligament reconstruction with artificial ligament in a rabbit model

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 29 ()

Background: Tunnel position deicide the isometry of graft attachment in synthetic anterior cruciate ligament (ACL) reconstruction. Near-isometric tunn......

De-osteogenic-differentiated mesenchymal stem cells accelerate fracture healing by mir-92b

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 ()

Background: Mesenchymal stem cells (MSCs) are promising targets for therapeutic use in regenerative medicine and tissue engineering. In the previous s......

Potential and recent advances of microcarriers in repairing cartilage defects

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 ()

Articular cartilage regeneration is one of the challenges faced by orthopedic surgeons. Microcarrier applications have made great advances in cartilag......

Reconstruction with customized, 3D-printed prosthesis after resection of periacetabular Ewing's sarcoma in children using "triradiate cartilage-based" surgical strategy:a technical note

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 28 ()

Background: Surgery for Ewing sarcoma involving acetabulum in children is challenging. Considering the intrinsic structure of immature pelvis, trans-a......

Design, reliability, and validity of a portable electronic device based on ergonomics for early screening of adolescent scoliosis

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 28 ()

Background/objective: The reported incidence of scoliosis among adolescents in China differs according to screening method owing to the lack of unifor......

Improved Ilizarov method for management of deformity and ulceration on foot and ankle of spina bifida

期刊: JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 28 ()

Objective: To analyze the characteristics of foot and ankle deformity with ulceration in patients with spina bifida, to conclude experiences on manage......

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