Molecular mechanisms of osteogenesis and antibacterial activity of Cu-bearing Ti alloy in a bone defect model with infection in vivo

Yang, J; Qin, HJ; Chai, Y; Zhang, P; Chen, YR; Yang, K; Qin, M; Zhang, YF; Xia, H; Ren, L; Yu, B

Yu, B (corresponding author), Southern Med Univ, Guangdong Prov Key Lab Bone & Cartilage Regenerat, Nanfang Hosp, Dept Orthopaed, Guangzhou 510515, Guangdong, Peoples R China.; Ren, L (corresponding author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China.; Xia, H (corresponding author), Guangzhou Mil Command PLA, Guangdong Key Lab Orthopaed Technol & Implant Mat, Key Lab Trauma & Tissue Repair Trop Area PLA, Dept Orthopaed,Guangzhou Gen Hosp, Guangzhou 510010, Peoples R China.

JOURNAL OF ORTHOPAEDIC TRANSLATION, 2021; 27 (): 77

Abstract

Objective: The antibacterial activity of copper (Cu)-alloy biomaterials has shown a great potential in clinical application. Here, we evaluated the os......

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