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Inhibiting Ferroptosis through Disrupting the NCOA4-FTH1 Interaction: A New Mechanism of Action

期刊: ACS CENTRAL SCIENCE, 2021; 7 (6)

Ferroptosis is an iron-dependent form of oxidative cell death, and the inhibition of ferroptosis is a promising strategy with which to prevent and tre......

Task-Specific Tailored Cationic Polymeric Network with High Base-Resistance for Unprecedented (TcO4-)-Tc-99 Cleanup from Alkaline Nuclear Waste

期刊: ACS CENTRAL SCIENCE, 2021; 7 (8)

Direct removal of (TcO4-)-Tc-99 from alkaline nuclear waste is desirable because of the nuclear waste management and environmental protection relevant......

Great Amplification of Circular Polarization Sensitivity via Heterostructure Engineering of a Chiral Two-Dimensional Hybrid Perovskite Crystal with a Three-Dimensional MAPbI(3) Crystal

期刊: ACS CENTRAL SCIENCE, 2021; 7 (7)

Chiral hybrid perovskites have brought an unprecedented opportunity for circularly polarized light (CPL) detection. However, the circular polarization......

Molecular Aspects Concerning the Use of the SARS-CoV-2 Receptor Binding Domain as a Target for Preventive Vaccines

期刊: ACS CENTRAL SCIENCE, 2021; 7 (5)

The development of recombinant COVID-19 vaccines has resulted from scientific progress made at an unprecedented speed during 2020. The recombinant spi......

Dual-Selective Catalysis in Dephosphorylation Tuned by Hf-6-Containing Metal-Organic Frameworks Mimicking Phosphatase

期刊: ACS CENTRAL SCIENCE, 2021; 7 (5)

Selective dephosphorylation is full of great challenges in the field of biomimetic catalysis. To mimic the active sites of protein phosphatase, Hf-OH-......

Unleashing the Power of Bond Cleavage Chemistry in Living Systems

期刊: ACS CENTRAL SCIENCE, 2021; 7 (6)

Bioorthogonal cleavage chemistry has been rapidly emerging as a powerful tool for manipulation and gain-of-function studies of biomolecules in living ......

Large-Scale Production of Hierarchically Porous Metal-Organic Frameworks by a Reflux-Assisted Post-Synthetic Ligand Substitution Strategy

期刊: ACS CENTRAL SCIENCE, 2021; 7 (8)

The mass production of hierarchically porous metal-organic frameworks (HP-MOFs) with adjustable morphology and size as well as retained crystallinity ......

Base-Resolution Analysis of Deoxyuridine at the Genome Scale Based on the Artificial Incorporation Modified Nucleobase

期刊: ACS CENTRAL SCIENCE, 2021; 7 (6)

Deamination of cytosine and dUMP misincorporation have been found to be capable of producing uracil in the genome. This study presents the Al-seq (art......

Rational Design of Poly(disulfide)s as a Universal Platform for Delivery of CRISPR-Cas9 Machineries toward Therapeutic Genome Editing

期刊: ACS CENTRAL SCIENCE, 2021; 7 (6)

We synthesized a series of poly(disulfide)s by ring-opening polymerization and demonstrated that the copolymerization of monomer 1 containing diethyle......

Constructing Well-Defined and Robust Th-MOF-Supported Single-Site Copper for Production and Storage of Ammonia from Electroreduction of Nitrate

期刊: ACS CENTRAL SCIENCE, 2021; 7 (6)

A combined technique of production and storage of ammonia (NH3) from electroreduction of nitrate (NO3) through one material is highly desirable but re......

Reconstructing Soma-Soma Synapse-like Vesicular Exocytosis with DNA Origami

期刊: ACS CENTRAL SCIENCE, 2021; 7 (8)

Cell-cell communications exhibit distinct physiological functions in immune responses and neurotransmitter signaling. Nevertheless, the ability to rec......

Advances in Catalytic Asymmetric Dearomatization

期刊: ACS CENTRAL SCIENCE, 2021; 7 (3)

Asymmetric catalysis has been recognized as the most enabling strategy for accessing chiral molecules in enantioenriched forms. Catalytic asymmetric d......

Dynamic Activation of C1 Molecules Evoked by Zeolite Catalysis

期刊: ACS CENTRAL SCIENCE, 2021; 7 (4)

Direct observation of the activation and transformation of reactant molecules is extremely attractive but very challenging in the study of most chemic......

Azo-Enhanced Raman Scattering for Enhancing the Sensitivity and Tuning the Frequency of Molecular Vibrations

期刊: ACS CENTRAL SCIENCE, 2021; 7 (5)

Raman scattering provides stable narrow-banded signals that potentially allow for multicolor microscopic imaging. The major obstacle for the applicati......

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