Rational Design of Poly(disulfide)s as a Universal Platform for Delivery of CRISPR-Cas9 Machineries toward Therapeutic Genome Editing

Guo, JJ; Wan, T; Li, BW; Pan, Q; Xin, HH; Qiu, YY; Ping, Y

Ping, Y (corresponding author), Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310058, Peoples R China.; Ping, Y (corresponding author), Zhejiang Univ, Liangzhu Lab, Med Ctr, Hangzhou 311121, Peoples R China.

ACS CENTRAL SCIENCE, 2021; 7 (6): 990

Abstract

We synthesized a series of poly(disulfide)s by ring-opening polymerization and demonstrated that the copolymerization of monomer 1 containing diethyle......

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