筛选条件 共查询到15条结果
排序方式
MicroRNA miR-627-5p restrains pulmonary artery smooth muscle cell dysfunction by targeting MAP 2K4 and PI3K/AKT signaling

期刊: GENES AND ENVIRONMENT, 2022; 44 (1)

Background: Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary vascular remodeling, which can be caused by abnormal proliferat......

Associations of maternal exposure to fine particulate matter with preterm and early-term birth in high-risk pregnant women

期刊: GENES AND ENVIRONMENT, 2022; 44 (1)

Background Environmental pollution is a risk factor for adverse birth outcomes, especially preterm birth (PTB) and early-term birth (ETB). It has been......

SIRT1 mediates nutritional regulation of SREBP-1c-driven hepatic PNPLA3 transcription via modulation of H3k9 acetylation

期刊: GENES AND ENVIRONMENT, 2022; 44 (1)

Background: Patatin-like phospholipase domain containing 3 (PNPLA3) is the main nonalcoholic fatty liver disease (NAFLD) susceptibility. Its expressio......

The establishment, development and future of the Chinese environmental mutagen society

期刊: GENES AND ENVIRONMENT, 2022; 44 (1)

It has been 40 years since the Chinese Environmental Mutagen Society (CEMS) was established in 1981. Now, it has grown a first-level national society ......

1,3-Butadiene: a ubiquitous environmental mutagen and its associations with diseases

期刊: GENES AND ENVIRONMENT, 2022; 44 (1)

1,3-Butadiene (BD) is a petrochemical manufactured in high volumes. It is a human carcinogen and can induce lymphohematopoietic cancers, particularly ......

Unique characteristics of G719X and S7681 compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China

期刊: GENES AND ENVIRONMENT, 2022; 44 (1)

Background: The principal objective of this project was to investigate the Epidermal Growth Factor Receptor (EGFR) gene mutation characteristics of lu......

Vitamin D receptor gene polymorphisms and its interactions with environmental factors on renal cell carcinoma risk

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Aims: We designed a case-control study to investigate the effect of vitamin D receptor gene (VDR) gene single nucleotide polymorphisms (SNPs) and poss......

New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Background Gene mutation assays in transgenic rodents are useful tools to investigate in vivo mutagenicity in a target tissue. Using a lambda EG10 tra......

Transcription factor 7-like 2 gene- smoking interaction on the risk of diabetic nephropathy in Chinese Han population

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Objectives: To evaluate the relationship between transcription factor 7-like 2 (TCF7L2) gene polymorphism and diabetic nephropathy (DN) risk, as well ......

Association of apolipoprotein B XbaI (rs693) polymorphism and gallstone disease risk based on a comprehensive analysis

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Background: Our aim was to investigate the association between XbaI gene polymorphisms in the apolipoprotein B (APOB) gene and gallstone disease (GD) ......

Dynamic assessing silica particle-induced pulmonary fibrosis and associated regulation of long non-coding RNA expression in Wistar rats

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Background: Exposure to respirable crystalline silica (RCS) can induce accelerated silicosis (AS), a form of silicosis that is more progressive and se......

Gene expression analysis in NSAID-induced rat small intestinal disease model with the intervention of berberine by the liquid chip technology

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Objective: Investigate the effect and mechanism of berberine on the small intestinal mucosa of non-steroidal anti-inflammatory drugs (NSAIDs) related ......

miR221 regulates cell migration by targeting annexin a1 expression in human mesothelial MeT-5A cells neoplastic-like transformed by multi-walled carbon nanotube

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Background: Multi-walled carbon nanotube (MWCNT) is one of the most widely used manufactured nanomaterials, however, its potential harmful effect on h......

The ACE and ACTN3 polymorphisms in female soccer athletes

期刊: GENES AND ENVIRONMENT, 2021; 43 (1)

Objects: We investigated the association of ACE I/D and ACTN3 R577X polymorphisms with the performance of Chinese elite female soccer athletes for the......

Using FFPE RNA-Seq with 12 marker genes to evaluate genotoxic and non-genotoxic rat hepatocarcinogens

期刊: GENES AND ENVIRONMENT, 2020; 42 (1)

Introduction Various challenges have been overcome with regard to applying 'omics technologies for chemical risk assessments. Previously we published ......

共15条页码: 1/1页15条/页