New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay

Masumura, K; Ando, T; Ukai, A; Fujiwara, S; Yokose, S; You, XY; Suzuki, T; Hayashi, H; Nohmi, T; Takagi, H; Honma, M

Masumura, K (corresponding author), Natl Inst Hlth Sci, Div Genet & Mutagenesis, Kawasaki Ku, 3-25-26 Tonomachi, Kawasaki, Kanagawa 2109501, Japan.

GENES AND ENVIRONMENT, 2021; 43 (1):

Abstract

Background Gene mutation assays in transgenic rodents are useful tools to investigate in vivo mutagenicity in a target tissue. Using a lambda EG10 tra......

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