期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2021; 35 (5)
Background Methotrexate (MTX) is used as anchor drug for patients with early and established rheumatoid arthritis (RA). Vitamin K-2 administration was......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, ; ()
Ulcerative colitis is a chronic inflammatory bowel disorder, which is having higher mortality rate. The present report evaluates the protective effect......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, ; ()
Sepsis-induced cerebral injury is a systemic inflammatory response associated with high mortality rate and cognitive impairment. Rho/ROCK pathway acti......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, ; ()
Glutamate excitotoxicity in cerebral ischemia/reperfusion is an important cause of neurological damage. The aim of this study was to investigate the m......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, ; ()
Hydrogen sulfide (H2S) represents the third and the youngest member of the gaseous transmitters family. The dominant effect of H2S on isolated vessels......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2021; 35 (1)
Fentanyl is a common sedative/analgesic used for intrathecal chemotherapy injection in children with acute leukemia. Given the contradictory findings ......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (6)
Omentin-1 is an adipokine expressed by the adipose tissue and is reduced in obesity. This study was designed to calculate the protective efficiency an......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (6)
The present study explored the role and mechanisms of mineralocorticoid receptor antagonists in beta-amyloid (A beta)-induced cognitive impairment. A ......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (1)
Cellular senescence, a state of irreversible growth arrest, occurs in all somatic cells and causes the cells to exhaust replicative capacity. Recently......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (1)
Aberrant activation of GTPases is common in cervical cancer, and their proper biological functions largely depend on a post-translational modification......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (4)
Visceral hypersensitivity (VH) is common in irritable bowel syndrome (IBS), and female patients are more likely to seek healthcare services for IBS-re......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (5)
The aim of this study was to estimate whether methotrexate (MTX) promotes cognitive impairment via increased ER stress and disrupted H2S signaling in ......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (5)
Exopolysaccharide fromAphanothece halophytica(EPSAH), a potent antitumor agent and immunological adjuvant, was investigated for the activation effect ......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (6)
This study aimed to investigate the role of ANXA13 in lung adenocarcinoma (LUAD) growth, migration, and the underlying mechanisms. Firstly, in the TCG......
期刊: FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2020; 34 (2)
Microglial inflammation leads to the upregulation of proinflammatory cytokine and proinflammatory enzyme expression, resulting in inflammation-induced......