Effects of vitamin K-2 combined with methotrexate against mitogen-activated peripheral blood mononuclear cells of healthy subjects and rheumatoid arthritis patients

Xu, WC; Wu, HG; Tahara, K; Chen, SH; Wang, XQ; Tanaka, S; Sugiyama, K; Sawada, T; Hirano, T

Sugiyama, K (corresponding author), Tokyo Univ Pharm & Life Sci, Sch Pharm, Dept Clin Pharmacol, 1432-1 Horinouchi, Hachioji, Tokyo 1920392, Japan.

FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2021; 35 (5): 832

Abstract

Background Methotrexate (MTX) is used as anchor drug for patients with early and established rheumatoid arthritis (RA). Vitamin K-2 administration was......

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