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Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Background Sepsis involves life-threatening organ dysfunction and is caused by a dysregulated host response to infection. No specific therapies agains......

JIF:2.58

mRNA vaccine development for cholangiocarcinoma: a precise pipeline

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Cholangiocarcinoma (CHOL) is one of the most aggressive tumors worldwide and cannot be effectively treated by conventional and novel treatments, inclu......

JIF:2.58

Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour immune microenvironment (TIME). This review focuses on the a......

JIF:2.58

Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Background Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that can occur when the blood supply to the ischemic brain t......

JIF:2.58

Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Non-muscle invasive bladder cancer (NMIBC) is a major type of bladder cancer with a high incidence worldwide, resulting in a great disease burden. Tre......

JIF:2.58

Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host re......

JIF:2.58

FGF2 is overexpressed in asthma and promotes airway inflammation through the FGFR/MAPK/NF-kappa B pathway in airway epithelial cells

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Background Airway inflammation is the core pathological process of asthma, with the key inflammatory regulators incompletely defined. Recently, fibrob......

JIF:2.58

N-6-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Background Stemness and chemoresistance contribute to cervical cancer recurrence and metastasis. In the current study, we determined the relevant play......

JIF:2.58

Gastrointestinal dysfunction is associated with mortality in severe burn patients: a 10-year retrospective observational study from South China

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Background Data on severe and extensive burns in China are limited, as is data on the prevalence of a range of related gastrointestinal (GI) disorders......

JIF:2.58

Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia (2021 Edition)

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health,......

JIF:2.58

Activation-induced pyroptosis contributes to the loss of MAIT cells in chronic HIV-1 infected patients

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Background Mucosal-associated invariant T (MAIT) cells are systemically depleted in human immunodeficiency virus type 1 (HIV-1) infected patients and ......

JIF:2.58

Advances in electrical impedance tomography-based brain imaging

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease d......

JIF:2.58

Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives

期刊: MILITARY MEDICAL RESEARCH, 2022; 9 (1)

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is associated with poor prognosis. Its characteristics of being......

JIF:2.58

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