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Genomic profiling in amyloid light-chain amyloidosis reveals mutation profiles associated with overall survival

期刊: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2020; 27 (1)

Background: Amyloid light chain (AL) amyloidosis is characterized by tissue deposition of amyloid fibres derived from immunoglobulin that can lead to ......

Regional amyloid distribution and impact on mortality in light-chain amyloidosis: a T1 mapping cardiac magnetic resonance study

期刊: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2019; 26 (1)

Background: T1 mapping allows quantitative assessment of diffuse deposition of amyloid protein in the myocardium. Early detection of cardiac involveme......

JIF:4.92

Bortezomib-based chemotherapy reduces early mortality and improves outcomes in patients with ultra-high-risk light-chain amyloidosis: a retrospective case control study

期刊: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2019; 26 (2)

Background: Patients with amyloid light-chain (AL) amyloidosis who have advanced cardiac damage are at risk of premature mortality. Currently, bortezo......

JIF:4.92

Light-chain amyloidosis with renal involvement: renal outcomes and validation of two renal staging systems in the Chinese population

期刊: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2019; 26 (4)

Background: Renal involvement is one of the most common complications of light-chain (AL) amyloidosis. For evaluating renal prognosis, two staging sys......

JIF:4.92

CSP-1103 (CHF5074) stabilizes human transthyretin in healthy human subjects

期刊: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2017; 24 (1)

Hereditary amyloid polyneuropathy is a type of protein misfolding disease. Transthyretin (TTR) is a homotetrameric serum protein and TTR tetramer diss......

JIF:4.05

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