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Benchmark of site- and structure-specific quantitative tissue N-glycoproteomics for discovery of potential N-glycoprotein markers: a case study of pancreatic cancer

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (2)

Pancreatic cancer is a highly malignant tumor of the digestive tract that is difficult to diagnose and treat. It is more common in developed countries......

Immunomodulatory effects of four polysaccharides purified from Erythronium sibiricum bulb on macrophages

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (4)

Four neutral polysaccharides (ESBP1-1, ESBP1-2, ESBP2-1 and ESBP3-1) were successfully purified from the water extracted crude polysaccharides of Eryt......

Isolation, purification and structural characterization of two pectin-type polysaccharides from Coreopsis tinctoria Nutt. and their proliferation activities on RAW264.7 cells

期刊: GLYCOCONJUGATE JOURNAL, ; ()

Coreopsis tinctoria Nutt. (C.tinctoria) is an annual herb of the Compositae family with many health benefits, such as clearing heat, antioxidant and a......

40 years of glyco-polyacrylamide in glycobiology

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (1)

Polyacrylamide conjugates of glycans have long been widely used in many research areas of glycobiology, mainly for immobilizing glycans in solid-phase......

Recent advances in understanding the roles of sialyltransferases in tumor angiogenesis and metastasis

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (1)

Abnormal glycosylation is a common characteristic of cancer cells and there is a lot of evidence that glycans can regulate the biological behavior of ......

Structural analysis of glycosaminoglycans from Oviductus ranae

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (1)

Oviductus ranae (O.ran.) has been widely used as a tonic and a traditional animal-based Chinese medicine. O.ran. extracts have been reported to have n......

A novel acid polysaccharide from Boletus edulis: extraction, characteristics and antitumor activities in vitro

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (1)

A novel cold-water-soluble polysaccharide (BEP), with a molecular weight of 6.0 x 10(6) Da, was isolated from Boletus edulis. BEP consists of galactos......

Up-regulation of FUT8 inhibits TGF-beta 1-induced activation of hepatic stellate cells during liver fibrogenesis

期刊: GLYCOCONJUGATE JOURNAL, 2021; 38 (1)

Liver fibrosis is a continuous wound healing response caused by chronic liver injury, and the activation of hepatic stellate cells (HSCs) is considere......

Structural characterization and antioxidant potential of a novel exopolysaccharide produced by Bacillus velezensis SN-1 from spontaneously fermented Da-Jiang

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (3)

The aim of this study was to characterize the exopolysaccharide (EPS) produced by Bacillus velezensis SN-1 (B. velezensis SN-1) (EPS-SN-1), which was ......

Immunoregulation and antioxidant activities of a novel acidic polysaccharide from Radix Paeoniae Alba

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (3)

Radix Paeoniae Alba is widely used in Chinese traditional medicine to treat various diseases such as gastrointestinal disorders, immunomodulatory, can......

The preparation of a cold-water soluble polysaccharide fromGrifola frondosaand its inhibitory effects on MKN-45 cells

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (4)

In this study, a novel water soluble polysaccharide (named GFP-4) was extracted fromGrifola frondosaat 4(o)C, and its preliminary structure and inhibi......

The expression and functional analysis of the sialyl-T antigen in prostate cancer

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (4)

Aberrant glycosylation is a featured characteristic of cancer and plays a role in cancer pathology; thus an understanding of the compositions and func......

Structural characteristics and anti-complement activities of polysaccharides fromSargassum hemiphyllum

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (5)

Three polysaccharides (SH-1, SH-2 and SH-3) were purified from a brown macroalgea,Sargassum hemiphyllum. The autohydrolysis products from each polysac......

ChemicalO-sulfation ofN-sulfoheparosan: a route to rareN-sulfo-3-O-sulfoglucosamine and 2-O-sulfoglucuronic acid

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (5)

Heparosan, the capsular polysaccharide ofE. coliK5 is currently used as the starting material in the chemoenzymatic synthesis of heparan sulfate and t......

Sialidase substrates for Sialdiase assays-activity, specificity, quantification and inhibition

期刊: GLYCOCONJUGATE JOURNAL, 2020; 37 (5)

Sialidases are glycosidases responsible for the removal of sialic acid (Sia) residues (desialylation) from glycan portions of either glycoproteins or ......

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