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Recent Applications of Point-of-Care Devices for Glucose Detection on the Basis of Stimuli-Responsive Volume Phase Transition of Hydrogel

期刊: BIOCHIP JOURNAL, 2021; 15 (1)

Diabetes is a serious global disease that threatens more than 400 million people's health. Therefore, timely detection of body's glucose level becomes......

Reduction of Erythrocyte Fluid Adaptability Due to Cell Membrane Hardening Based on Single-Cell Analysis

期刊: BIOCHIP JOURNAL, 2021; 15 (1)

Because of the rapid development of precision medicine, single-cell analysis has attracted increasing research attention, especially for erythrocyte, ......

Next-Generation Sequencing-Based Preimplantation Genetic Testing for De Novo NF1 Mutations

期刊: BIOCHIP JOURNAL, 2021; 15 (1)

Neurofibroma type 1 (NFI) is an autosomal dominant genetic disease associated with cancer and cognitive dysfunction. The 50% de novo mutation rate and......

Separation of Macrophages Using a Dielectrophoresis-Based Microfluidic Device

期刊: BIOCHIP JOURNAL, 2020; 14 (2)

Macrophages are an important component of the immune system and play a key role in tissue damage repair and immune defense. As a potential biomarker, ......

A Numerical Study of Droplet Splitting using Different Spacers in EWOD Device

期刊: BIOCHIP JOURNAL, 2020; 14 (3)

In this paper, we investigated the droplet splitting using different spacers in the air. The droplets were manipulated by the EWOD force and the level......

Efficient Bond of PDMS and Printed Circuit Board with An Application on Continuous-flow Polymerase Chain Reaction

期刊: BIOCHIP JOURNAL, 2020; 14 (4)

A simple and efficient bond technique for integrating polydimethylsiloxane (PDMS) and printed circuit board (PCB) is presented in this paper by using ......

Simultaneous Multiplexed Detection of Protein and Metal Ions by a Colorimetric Microfluidic Paper-based Analytical Device

期刊: BIOCHIP JOURNAL, 2020; 14 (4)

In order to improve the efficiency of disease diagnosis and environmental monitoring, it is desirable to detect the concentration of proteins and meta......

Tradeoff Control of Multi-exposure Lithography for SU-8 Photochemical Reaction Channel Formation

期刊: BIOCHIP JOURNAL, 2020; 14 (4)

A method involving multi-exposure with low-power is presented to fabricate an SU-8 mold based on a digital micromirror device (DMD) maskless lithograp......

Preimplantation Genetic Testing of Achondroplasia by Two Haplotyping Systems: Short Tandem Repeats and Single Nucleotide Polymorphism

期刊: BIOCHIP JOURNAL, 2019; 13 (2)

Here, we present the successful application of two different preimplantation genetic testing for monogenic diseases (PGT-M) methods for a couple facin......

JIF:1.95

A Multichannel Electroosmotic Flow Pump Using Liquid Metal Electrodes

期刊: BIOCHIP JOURNAL, 2019; 13 (3)

Injecting a room-temperature liquid metal into microchannels offers a simple, rapid, and low-cost method of fabricating microfluidic electrodes. In th......

JIF:1.95

Label-free Microarray-based Binding Affinity Constant Measurement with Modified Fluidic Arrangement

期刊: BIOCHIP JOURNAL, 2018; 12 (1)

The oblique-incidence reflectivity difference (OI-RD) scanning microscopy has the capability of simultaneously measuring binding curves of a protein p......

JIF:1.95

Genome-wide Identification and Expression Analyses of RPP13-like Genes in Barley

期刊: BIOCHIP JOURNAL, 2018; 12 (2)

Plants have evolved a series of mechanisms to resist pathogens infection. The nucleotide-binding site and leucine-rich repeat (NBS-LRR) family contain......

JIF:1.95

A Microfluidic Hydrogel Chip with Orthogonal Dual Gradients of Matrix Stiffness and Oxygen for Cytotoxicity Test

期刊: BIOCHIP JOURNAL, 2018; 12 (2)

The oxygen tensions and matrix stiffness play important roles in regulating cell response to cytotoxic drugs. In recent years, single spatiotemporal o......

JIF:1.95

Joule Heating Effects on Two-phase Flows in Dielectrophoresis Microchips

期刊: BIOCHIP JOURNAL, 2017; 11 (3)

Joule heating is a significant phenomenon in dielectrophoresis-based microfluidic devices due to the local amplification of the electric field around ......

JIF:1.4

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