Increasing Dosage of Leucovorin Results in Pharmacokinetic and Gene Expression Differences When Administered as Two-Hour Infusion or Bolus Injection to Patients with Colon Cancer

Taflin, H; Odin, E; Carlsson, G; Gustavsson, B; Wettergren, Y; Lindskog, EB

Lindskog, EB (通讯作者)，Univ Gothenburg, Sahlgrenska Univ Hosp, Inst Clin Sci, Dept Surg,Sahlgrenska Acad, S-41685 Gothenburg, Sweden.

CANCERS, 2023; 15 (1):

Abstract

Simple Summary 5-fluorouracil (5-FU) is the drug used in almost all chemotherapy regimens for colorectal cancer. To potentiate the drug effect, 5-FU i......

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