The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy

Liu, H; Wei, J; Sang, N; Zhong, X; Zhou, X; Yang, XY; Zhang, J; Zuo, ZP; Zhou, Y; Yang, SY; Du, JR; Zhao, YL

Du, JR; Zhao, YL (corresponding author), Sichuan Univ, Dept Pharmacol, Key Lab Drug Targeting & Drug Delivery Syst, Educ Minist,Sichuan Engn Lab Plant Sourced Drug, Chengdu 610041, Peoples R China.; Du, JR; Zhao, YL (corresponding author), Sichuan Univ, Sichuan Res Ctr Drug Precis Ind Technol, West China Sch Pharm, Chengdu 610041, Peoples R China.; Zhao, YL (corresponding author), Sichuan Univ, State Key Lab Biotherapy & Canc Ctr, West China Hosp, West China Med Sch, Chengdu 610041, Peoples R Ch

MEDICAL ONCOLOGY, 2021; 38 (10):

Abstract

Lysine-specific demethylase 1 (LSD1, also known as KDM1A) is an attractive agent for treatment of cancer. However, the anti-tumor effect of LSD1 inhib......

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