A proline switch explains kinetic heterogeneity in a coupled folding and binding reaction

Zosel, F; Mercadante, D; Nettels, D; Schuler, B

Schuler, B (reprint author), Univ Zurich, Dept Biochem, Winterthurerstr 190, CH-8057 Zurich, Switzerland.; Schuler, B (reprint author), Univ Zurich, Dept Phys, Winterthurerstr 190, CH-8057 Zurich, Switzerland.

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

The interactions of intrinsically disordered proteins (IDPs) with their molecular targets are essential for the regulation of many cellular processes.......

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