BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

Cuyas, E; Corominas-Faja, B; Martin, MMS; Martin-Castillo, B; Lupu, R; Brunet, J; Bosch-Barrera, J; Menendez, JA

Menendez, JA (reprint author), Catalan Inst Oncol, Metab & Canc Grp, Program Canc Therapeut Resistance ProCURE, Girona, Catalonia, Spain.; Menendez, JA (reprint author), Girona Biomed Res Inst IDIBGI, Mol Oncol Grp, Girona, Catalonia, Spain.

ONCOTARGET, 2017; 8 (21): 35019

Abstract

Denosumab, a monoclonal antibody to the receptor activator of nuclear factor-kappa B ligand (RANKL), might be a novel preventative therapy for BRCA1-m......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索