Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers

Glodzik, D; Bosch, A; Hartman, J; Aine, M; Vallon-Christersson, J; Reutersward, C; Karlsson, A; Mitra, S; Nimeus, E; Holm, K; Hakkinen, J; Hegardt, C; Saal, LH; Larsson, C; Malmberg, M; Ryden, L; Ehinger, A; Loman, N; Kvist, A; Ehrencrona, H; Nik-Zainal, S; Borg, A; Staaf, J

Staaf, J (corresponding author), Lund Univ, Dept Clin Sci Lund, Div Oncol, SE-22381 Lund, Sweden.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Homologous recombination deficiency (HRD) is a defining characteristic in BRCA-deficient breast tumors caused by genetic or epigenetic alterations in ......

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