Reductase of Mutanobactin Synthetase Triggers Sequential C-C Macrocyclization, C-S Bond Formation, and C-C Bond Cleavage

Wang, M; Xie, ZJ; Tang, SB; Chang, EL; Tang, Y; Guo, ZY; Cui, YL; Wu, B; Ye, T; Chen, YH

Chen, YH (corresponding author), Chinese Acad Sci, Inst Microbiol, Beijing, Peoples R China.; Chen, YH (corresponding author), Univ Chinese Acad Sci, Beijing, Peoples R China.

ORGANIC LETTERS, 2020; 22 (3): 960

Abstract

Mutanobactins (MUBs) and their congeners that contain a macrocycle and/or a thiazepane ring are lipopeptides from Streptococcus mutans, a major causat......

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