Abrogation of FBW7 alpha-dependent p53 degradation enhances p53's function as a tumor suppressor

Tripathi, V; Kaur, E; Kharat, SS; Hussain, M; Damodaran, AP; Kulshrestha, S; Sengupta, S

Sengupta, S (reprint author), Natl Inst Immunol, Aruna Asaf Ali Marg, New Delhi 110067, India.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2019; 294 (36): 13224

Abstract

The gene encoding the tumor suppressor p53 is mutated in most cancers. p53 expression is known to be tightly controlled by several E3 ligases. Here, w......

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