HS218 as an FXR antagonist suppresses gluconeogenesis by inhibiting FXR binding to PGC-1 alpha promoter

Xu, X; Shi, XF; Chen, YD; Zhou, TT; Wang, JY; Xu, X; Chen, LL; Hu, LH; Shen, X

Hu, LH; Shen, X (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Research, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China.

METABOLISM-CLINICAL AND EXPERIMENTAL, 2018; 85 (): 126

Abstract

Introduction: Famesoid X receptor (FXR) as a member of nuclear receptor is tightly associated with glucose metabolism. Accumulated evidence has addres......

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