Dexmedetomidine reduces norepinephrine requirements and preserves renal oxygenation and function in ovine septic acute kidney injury

Lankadeva, YR; Ma, S; Iguchi, N; Evans, RG; Hood, SG; Farmer, DGS; Bailey, SR; Bellomo, R; May, CN

May, CN (reprint author), Univ Melbourne, Florey Inst Neurosci & Mental Hlth, 30 Royal Parade, Parkville, Vic 3052, Australia.

KIDNEY INTERNATIONAL, 2019; 96 (5): 1150

Abstract

Norepinephrine exacerbates renal medullary hypoxia in experimental septic acute kidney injury. Here we examined whether dexmedetomidine, an alpha 2-ad......

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