Topotecan reduces sepsis-induced acute lung injury and decreases the inflammatory response via the inhibition of the NF-kappa B signaling pathway

Wang, XX; Xu, TX; Jin, JJ; Gao, MMT; Wan, B; Gong, M; Bai, LX; Lv, TF; Song, Y

Lv, TF; Song, Y (通讯作者)，Jinling Hosp, Dept Resp & Crit Med, 305 East Zhongshan Rd, Nanjing 210002, Peoples R China.

PULMONARY CIRCULATION, 2022; 12 (2):

Abstract

This study aims to determine the function of topotecan (TPT) in acute lung injury (ALI) induced by sepsis. The mouse sepsis model was constructed thro......

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