Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma

Ennishi, D; Jiang, A; Boyle, M; Collinge, B; Grande, BM; Ben-Neriah, S; Rushton, C; Tang, J; Thomas, N; Slack, GW; Farinha, P; Takata, K; Miyata-Takata, T; Craig, J; Mottok, A; Meissner, B; Saberi, S; Bashashati, A; Villa, D; Savage, KJ; Sehn, LH; Kr

Scott, DW (reprint author), British Columbia Canc Res Ctr, 675 West 10th Ave,Room 12-112, Vancouver, BC V5Z 1L3, Canada.

JOURNAL OF CLINICAL ONCOLOGY, 2019; 37 (3): 190

Abstract

PurposeHigh-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We s......

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