CRL4B(DCAF11) E3 ligase targets p21 for degradation to control cell cycle progression in human osteosarcoma cells

Chen, Z; Wang, K; Hou, CL; Jiang, KB; Chen, B; Chen, JW; Lao, LF; Qian, L; Zhong, GB; Liu, ZD; Zhang, CG; Shen, HX

Shen, HX (reprint author), Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Dept Spine Surg, Shanghai, Peoples R China.; Zhang, CG (reprint author), Univ Colorado, Dept Dermatol, Anschutz Med Campus, Aurora, CO 80045 USA.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

Cell cycle progression in mammals is strictly controlled by a number of cyclin-dependent kinases (CDKs) and CDK inhibitors (CKIs), the expression of w......

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