RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP-MedSci.cn

RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP

Tsai, TY; Wang, WT; Li, HK; Chen, WJ; Tsai, YH; Chao, CH; Lee, YHW

Lee, YHW (reprint author), Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 300, Taiwan.; Lee, YHW (reprint author), Natl Yang Ming Univ, Inst Biochem & Mol Biol, Taipei 112, Taiwan.

Scientific Reports, 2017; 7 ( ):

Abstract

Multifunctional RNA helicase DDX3 participates in HCV infection, one of the major causes of hepatic steatosis. Here, we investigated the role of DDX3 ......

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