A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells

O'Brien, M; Moehring, D; Munoz-Planillo, R; Nunez, G; Callaway, J; Ting, J; Scurria, M; Ugo, T; Bernad, L; Cali, J; Lazar, D

O'Brien, M (reprint author), Promega Corp, 2800 Woods Hollow Rd, Madison, WI 53711 USA.

JOURNAL OF IMMUNOLOGICAL METHODS, 2017; 447 ( ): 1

Abstract

Inflammasomes are protein complexes induced by diverse inflammatory stimuli that activate caspase-1, resulting in the processing and release of cytoki......

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