Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab

Lee, HT; Lee, JY; Lim, H; Lee, SH; Moon, YJ; Pyo, HJ; Ryu, SE; Shin, W; Heo, YS

Heo, YS (reprint author), Konkuk Univ, Dept Chem, 120 Neungdong Ro, Seoul 05029, South Korea.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

In 2016 and 2017, monoclonal antibodies targeting PD-L1, including atezolizumab, durvalumab, and avelumab, were approved by the FDA for the treatment ......

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