A novel selective spleen tyrosine kinase inhibitor SKI-O-703 (cevidoplenib) ameliorates lupus nephritis and serum-induced arthritis in murine models

Cho, S; Jang, E; Yoon, T; Hwang, H; Youn, J

Jang, E; Youn, J (通讯作者)，Hanyang Univ, Coll Med, Dept Anat & Cell Biol, Lab Autoimmunol, 222 Wangsimni Ro, Seoul 04763, South Korea.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2023; 211 (1): 31

Abstract

Orally administered SKI-O-703, a new Syk inhibitor, reduces lupus nephritis-like manifestations in NZB/W mice. Spleen tyrosine kinase (Syk) plays a pi......

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