CRISPR/Cas9 Deletion of SOX2 Regulatory Region 2 (SRR2) Decreases SOX2 Malignant Activity in Glioblastoma

Saenz-Antonanzas, A; Moncho-Amor, V; Auzmendi-Iriarte, J; Elua-Pinin, A; Rizzoti, K; Lovell-Badge, R; Matheu, A

Matheu, A (corresponding author), Biodonostia Hlth Res Inst, Cellular Oncol Grp, San Sebastian 20014, Spain.; Matheu, A (corresponding author), Carlos III Inst, CIBER Frailty & Hlth Aging CIBERfes, Madrid 28029, Spain.; Matheu, A (corresponding author), Basque Fdn Sci, Ikerbasque, Bilbao 48009, Spain.

CANCERS, 2021; 13 (7):

Abstract

Simple Summary Understanding how SOX2, a major driver of cancer stem cells, is regulated in cancer cells is relevant to tackle tumorigenesis. In this ......

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