PRECLINICAL PHARMACOKINETIC ANALYSIS OF (E)-METHYL-4-ARYL-4-OXABUT-2-ENOATE, A NOVEL SER/THR PROTEIN KINASE B INHIBITOR, IN RATS

Zhai, QQ; Pang, J; Li, GQ; Li, CR; Wang, YC; Yu, LY; Li, J; You, XF

You, XF (reprint author), Chinese Acad Med Sci, Beijing Key Lab Antiinfect Agents, Inst Med Biotechnol, Beijing 100050, Peoples R China.; You, XF (reprint author), Peking Union Med Coll, Beijing 100050, Peoples R China.

ACTA POLONIAE PHARMACEUTICA, 2017; 74 (1): 299

Abstract

(E)-Methyl-l-aryl-4-oxabut-2-enoate. designated YH-8. is a novel Ser/Thr protein kinase B (PknB) inhibitor, which is designed for the treatment of tub......

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