Targeting the MAPK Pathway in RAS Mutant Cancers

Hymowitz, SG; Malek, S

Malek, S (reprint author), Genentech Inc, Dept Discovery Oncol, San Francisco, CA 94080 USA.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, 2018; 8 (11):

Abstract

Despite decades of extensive drug discovery efforts, there are currently no targeted therapies approved to treat KRAS mutant cancers. In this review, ......

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