TCR alpha beta/CD3 disruption enables CD3-specific antileukemic T cell immunotherapy

Rasaiyaah, J; Georgiadis, C; Preece, R; Mock, U; Qasim, W

Qasim, W (reprint author), UCL GOS Inst Child Hlth, Mol & Cellular Immunol Unit, United Kingdom Inst Child Hlth, London WC1N 1EH, England.

JCI INSIGHT, 2018; 3 (13):

Abstract

T cells engineered to express chimeric antigen receptors (CARs) against B cell antigens are being investigated as cellular immunotherapies. Similar ap......

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