In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants

Takano, S; Fukami, T; Ichida, H; Suzuki, K; Nakano, M; Nakajima, M

Fukami, T (通讯作者)，Kanazawa Univ, Fac Pharmaceut Sci, Drug Metab & Toxicol, Kakuma Machi, Kanazawa 9201192, Japan.

DRUG METABOLISM AND DISPOSITION, 2023; 51 (9): 1188

Abstract

Aldo-keto reductase 1C3 (AKR1C3) plays a role in the detoxification and activation of clinical drugs by catalyzing reduction reactions. There are appr......

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