Uncovering universal rules governing the selectivity of the archetypal DNA glycosylase TDG

Dodd, T; Yan, CL; Kossmann, BR; Martin, K; Ivanov, I

Ivanov, I (reprint author), Georgia State Univ, Dept Chem, Atlanta, GA 30302 USA.; Ivanov, I (reprint author), Georgia State Univ, Ctr Diagnost & Therapeut, Atlanta, GA 30302 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018; 115 (23): 5974

Abstract

Thymine DNA glycosylase (TDG) is a pivotal enzyme with dual roles in both genome maintenance and epigenetic regulation. TDG is involved in cytosine de......

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