EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis

Sala, C; Odermatt, NT; Soler-Arnedo, P; Gulen, MF; von Schultz, S; Benjak, A; Cole, ST

Sala, C; Cole, ST (reprint author), Ecole Polytech Fed Lausanne, Global Hlth Inst, Lausanne, Switzerland.; Cole, ST (reprint author), Inst Pasteur, Paris, France.

PLOS PATHOGENS, 2018; 14 (12):

Abstract

The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellul......

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