Exploring the Lower Limit of Individual DNA-Encoded Library Molecules in Selection

Chen, QX; Cheng, XM; Zhang, LF; Li, XY; Chen, PR; Liu, J; Zhang, LJ; Wei, H; Li, ZH; Dou, DF

Dou, DF (reprint author), HitGen Inc, Lead Generat Unit, 8 Huigu 1st East Rd, Chengdu 610200, Sichuan, Peoples R China.; Li, ZH (reprint author), Sichuan Univ, Coll Life Sci, 29 Wangjiang Rd, Chengdu 610065, Sichuan, Peoples R China.

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Abstract

DNA-encoded library (DEL) technology has been used as an ultra-high-throughput screening approach for hit identification of drug targets. This process......

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