Evaluation of Intracellular Metabolism of Methotrexate in Hepatocytes and Embryonic Kidney Cells based on Folylpolyglutamate Synthetase and Gamma-Glutamyl Hydrolase Expression

Jiang, HB; Yang, J; Hou, YC; Zhang, K; Ren, Y; Huang, J; Li, HH; Cai, TJ; Ouyang, ZH; Zhao, J; Yu, P

Jiang, HB; Yang, J; Yu, P (通讯作者)，Cent South Univ, Xiangya Sch Pharmaceut Sci, 172,Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

CURRENT DRUG METABOLISM, 2023; 24 (2): 139

Abstract

Background: Methotrexate (MTX) is a common folic acid antagonist in clinical medicine, easily inducing a common adverse side effect of liver and kidne......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索